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The number of titrated microRNA species dictates ceRNA regulation

microRNAs (miRNAs) play key roles in cancer, but their propensity to couple their targets as competing endogenous RNAs (ceRNAs) has only recently emerged. Multiple models have studied ceRNA regulation, but these models did not account for the effects of co-regulation by miRNAs with many targets. We...

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Detalles Bibliográficos
Autores principales: Chiu, Hua-Sheng, Martínez, María Rodríguez, . Komissarova, Elena V, Llobet-Navas, David, Bansal, Mukesh, Paull, Evan O, Silva, José, Yang, Xuerui, Sumazin, Pavel, Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961349/
https://www.ncbi.nlm.nih.gov/pubmed/29684207
http://dx.doi.org/10.1093/nar/gky286