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Dissecting the sources of gene expression variation in a pan-cancer analysis identifies novel regulatory mutations

Although the catalog of cancer-associated mutations in protein-coding regions is nearly complete for all major cancer types, an assessment of regulatory changes in cancer genomes and their clinical significance remain largely preliminary. Adopting bottom-up approach, we quantify the effects of diffe...

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Detalles Bibliográficos
Autores principales: Sharma, Anchal, Jiang, Chuan, De, Subhajyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961375/
https://www.ncbi.nlm.nih.gov/pubmed/29672706
http://dx.doi.org/10.1093/nar/gky271