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Dissecting the sources of gene expression variation in a pan-cancer analysis identifies novel regulatory mutations
Although the catalog of cancer-associated mutations in protein-coding regions is nearly complete for all major cancer types, an assessment of regulatory changes in cancer genomes and their clinical significance remain largely preliminary. Adopting bottom-up approach, we quantify the effects of diffe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961375/ https://www.ncbi.nlm.nih.gov/pubmed/29672706 http://dx.doi.org/10.1093/nar/gky271 |