Cargando…

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

De novo and acquired resistance, largely attributed to genetic alterations, are barriers to effective anti-EGFR therapy. We generated cetuximab-resistant cells following prolonged cetuximab exposure to cetuximab-sensitive colorectal cancer cells in three-dimensional culture. Through whole exome sequ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yuanyuan, Zhao, Xiaodi, Liu, Qi, Li, Cunxi, Graves-Deal, Ramona, Cao, Zheng, Singh, Bhuminder, Franklin, Jeffrey L., Wang, Jing, Hu, Huaying, Wei, Tianying, Yang, Mingli, Yeatman, Timothy J., Lee, Ethan, Saito-Diaz, Kenyi, Hinger, Scott, Patton, James G., Chung, Christine H., Emmrich, Stephan, Klusmann, Jan-Henning, Fan, Daiming, Coffey, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961502/ https://www.ncbi.nlm.nih.gov/pubmed/29035371 http://dx.doi.org/10.1038/nm.4424

Ejemplares similares

LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia
por: Emmrich, Stephan, et al.
Publicado: (2014)

miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44
por: Sun, Lina, et al.
Publicado: (2019)

miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma
por: Kubota, Daisuke, et al.
Publicado: (2016)

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b
por: Vergani, Elisabetta, et al.
Publicado: (2015)

Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma
por: Torres, Anna, et al.
Publicado: (2012)

The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression
por: Wu, Weining, et al.
Publicado: (2019)

miR-100 Inhibits the Growth and Migration of Burn-Denatured Fibroblasts
por: Ying, Jianghui, et al.
Publicado: (2016)

The role of miR-100 in regulating apoptosis of breast cancer cells
por: Gong, Yi, et al.
Publicado: (2015)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

Plasma miR-200c-3p, miR-100-5p, and miR-1826 serve as potential diagnostic biomarkers for knee osteoarthritis: Randomized controlled trials
por: Lai, Zhen, et al.
Publicado: (2019)

miR-143 and miR-145 inhibit gastric cancer cell migration and metastasis by suppressing MYO6
por: Lei, Chao, et al.
Publicado: (2017)

miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF
por: Varendi, Kärt, et al.
Publicado: (2014)

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
por: Qiu, Shuwei, et al.
Publicado: (2013)

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
por: Schee, Kristina, et al.
Publicado: (2012)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma
por: Loosen, Sven H., et al.
Publicado: (2019)

Generation and Validation of miR-100 Hepatocyte-Specific Knock-Out Mice
por: Yang, Dong, et al.
Publicado: (2019)

Expression and Related Mechanisms of miR-100 and TRIB2 in COPD Patients
por: Mai, Zhitao, et al.
Publicado: (2022)

miR-99a/100∼125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling
por: Emmrich, Stephan, et al.
Publicado: (2014)

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
por: Nemecz, Miruna, et al.
Publicado: (2023)

miR-497/MIR497HG inhibits glioma cell proliferation by targeting CCNE1 and the miR-588/TUSC1 axis
por: Ji, Li-Ya, et al.
Publicado: (2021)

miR-100 inhibits the migration and invasion of nasopharyngeal carcinoma by targeting IGF1R
por: Sun, Xiaoyan, et al.
Publicado: (2018)

Elevated Serum miR-7, miR-9, miR-122, and miR-141 Are Noninvasive Biomarkers of Acute Pancreatitis
por: Lu, Pan, et al.
Publicado: (2017)

Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma
por: Seol, Hyang Sook, et al.
Publicado: (2020)

MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome
por: Wang, Yuluan, et al.
Publicado: (2020)

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging
por: Hackl, Matthias, et al.
Publicado: (2010)

MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression
por: Unterbruner, Kristoffer, et al.
Publicado: (2018)

The clinical significance of circulating miR-21, miR-142, miR-143, and miR-146a in patients with prostate cancer
por: Bolayırlı, Ibrahim Murat, et al.
Publicado: (2022)

miR-496, miR-1185, miR-654, miR-3183 and miR-495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway
por: Alqurashi, Naif, et al.
Publicado: (2019)

LncRNA miR143HG Up-Regulates p53 In Endometrial Carcinoma By Sponging miR-125a
por: Shi, Fan, et al.
Publicado: (2019)

LncRNA MIR100HG promotes cancer cell proliferation, migration and invasion in laryngeal squamous cell carcinoma through the downregulation of miR-204-5p
por: Huang, Yongyang, et al.
Publicado: (2019)

miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion
por: Chen, Dahu, et al.
Publicado: (2014)

Association of miR-100 expression with clinicopathological features and prognosis of patients with lung cancer
por: Ma, Xiaolong, et al.
Publicado: (2019)

Retracted: Expression and Related Mechanisms of miR-100 and TRIB2 in COPD Patients
por: Healthcare Engineering, Journal of
Publicado: (2023)

Post-transcriptional Regulation of PCSK9 by miR-191, miR-222, and miR-224
por: Naeli, Parisa, et al.
Publicado: (2017)

FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b
por: Coccia, Elena, et al.
Publicado: (2020)

Expression of miR-127, miR-154, and miR-183 in Medullary Thyroid Carcinoma Tumors
por: RAHMANI SAMANI, Mahsa, et al.
Publicado: (2021)

Expression of miR-210, miR-137, and miR-153 in Patients with Acute Cerebral Infarction
por: Tian, Hongtao, et al.
Publicado: (2021)

Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC
por: Fornari, Francesca, et al.
Publicado: (2015)

Differential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
por: Mosapour, Abbas, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dvmsn00k58js66bnjs3o31t7a7