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Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study

OBJECTIVE: To determine whether autologous infusions of expanded regulatory T lymphoctyes (Tregs) into patients with amyotrophic lateral sclerosis (ALS) are safe and tolerable during early and later stages of disease. METHODS: Three patients with ALS, with no family history of ALS, were selected bas...

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Detalles Bibliográficos
Autores principales: Thonhoff, Jason R., Beers, David R., Zhao, Weihua, Pleitez, Milvia, Simpson, Ericka P., Berry, James D., Cudkowicz, Merit E., Appel, Stanley H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961523/
https://www.ncbi.nlm.nih.gov/pubmed/29845093
http://dx.doi.org/10.1212/NXI.0000000000000465