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Assembly of 809 whole mitochondrial genomes with clinical, imaging, and fluid biomarker phenotyping

INTRODUCTION: Mitochondrial genetics are an important but largely neglected area of research in Alzheimer’s disease. A major impediment is the lack of data sets. METHODS: We used an innovative, rigorous approach, combining several existing tools with our own, to accurately assemble and call variants...

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Detalles Bibliográficos
Autores principales: Ridge, Perry G., Wadsworth, Mark E., Miller, Justin B., Saykin, Andrew J., Green, Robert C., Kauwe, John S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961720/
https://www.ncbi.nlm.nih.gov/pubmed/29306584
http://dx.doi.org/10.1016/j.jalz.2017.11.013