Cargando…

Exploring Landscape of Drug-Target-Pathway-Side Effect Associations

Side effects are the second and the fourth leading causes of drug attrition and death in the US. Thus, accurate prediction of side effects and understanding their mechanism of action will significantly impact drug discovery and clinical practice. Here, we show REMAP, a neighborhood-regularized weigh...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Hansaim, Poleksic, Aleksandar, Xie, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961812/
https://www.ncbi.nlm.nih.gov/pubmed/29888057