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Exploring Landscape of Drug-Target-Pathway-Side Effect Associations
Side effects are the second and the fourth leading causes of drug attrition and death in the US. Thus, accurate prediction of side effects and understanding their mechanism of action will significantly impact drug discovery and clinical practice. Here, we show REMAP, a neighborhood-regularized weigh...
Autores principales: | Lim, Hansaim, Poleksic, Aleksandar, Xie, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Informatics Association
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961812/ https://www.ncbi.nlm.nih.gov/pubmed/29888057 |
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