Ubiquitin-dependent proteolysis of CXCL7 leads to posterior longitudinal ligament ossification

Ossification of the posterior longitudinal ligament (OPLL), a spinal ligament, reduces the range of motion in limbs. No treatment is currently available for OPLL, which is why therapies are urgently needed. OPLL occurs in obesity, is more common in men, and has an onset after 40 years of age. The me...

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Detalles Bibliográficos
Autores principales: Tsuru, Michiyo, Ono, Atsushi, Umeyama, Hideaki, Takeuchi, Masahiro, Nagata, Kensei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962073/
https://www.ncbi.nlm.nih.gov/pubmed/29782494
http://dx.doi.org/10.1371/journal.pone.0196204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962073/
https://www.ncbi.nlm.nih.gov/pubmed/29782494
http://dx.doi.org/10.1371/journal.pone.0196204

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