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Ubiquitin-dependent proteolysis of CXCL7 leads to posterior longitudinal ligament ossification
Ossification of the posterior longitudinal ligament (OPLL), a spinal ligament, reduces the range of motion in limbs. No treatment is currently available for OPLL, which is why therapies are urgently needed. OPLL occurs in obesity, is more common in men, and has an onset after 40 years of age. The me...
Autores principales: | Tsuru, Michiyo, Ono, Atsushi, Umeyama, Hideaki, Takeuchi, Masahiro, Nagata, Kensei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962073/ https://www.ncbi.nlm.nih.gov/pubmed/29782494 http://dx.doi.org/10.1371/journal.pone.0196204 |
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