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Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer

BACKGROUND: Chemotherapy is still the primary adjuvant strategy of cancer therapy; however, the emergence of multi-drug resistance has been a cause for concern. Autophagy has been demonstrated to have a protective role against chemotherapeutic drugs in cancer cells, and autophagy inhibition is gener...

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Detalles Bibliográficos
Autores principales: Lu, Xiao, Zhou, Dong, Hou, Bing, Liu, Quan-Xing, Chen, Qian, Deng, Xu-Feng, Yu, Zu-Bin, Dai, Ji-Gang, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962308/
https://www.ncbi.nlm.nih.gov/pubmed/29844702
http://dx.doi.org/10.2147/CMAR.S156530