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Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock

Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role of the sclerotome in establishing the axial skeleton is unclear. We severely disrupt zebrafis...

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Detalles Bibliográficos
Autores principales: Lleras Forero, Laura, Narayanan, Rachna, Huitema, Leonie FA, VanBergen, Maaike, Apschner, Alexander, Peterson-Maduro, Josi, Logister, Ive, Valentin, Guillaume, Morelli, Luis G, Oates, Andrew C, Schulte-Merker, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962341/
https://www.ncbi.nlm.nih.gov/pubmed/29624170
http://dx.doi.org/10.7554/eLife.33843