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Neuromodulation of orexin neurons reduces diet-induced adiposity

BACKGROUND/OBJECTIVES: Low levels of orexin are associated with obesity and reduced physical activity in humans and animals. SUBJECTS/METHODS: Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) selectively activated orexin neurons in mouse lateral hypothalamus (LH) to measure effec...

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Detalles Bibliográficos
Autores principales: Zink, A N, Bunney, P E, Holm, A A, Billington, C J, Kotz, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962366/
https://www.ncbi.nlm.nih.gov/pubmed/29180723
http://dx.doi.org/10.1038/ijo.2017.276