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Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma

Constant exposure to allergen triggers destructive type 2 cell-mediated inflammation. The effect of allergen specific immunotherapy (SIT) in maintaining airway epithelial barrier function in asthma remains unknown. In the current study, we showed that SIT maintained airway epithelial homeostasis in...

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Detalles Bibliográficos
Autores principales: Yuan, Xiefang, Wang, Junyi, Li, Yin, He, Xiang, Niu, Bin, Wu, Dehong, lan, Nan, Wang, Xiaoyun, Zhang, Yun, Dai, Xi, Wang, Xing, Liu, Zhigang, Li, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962552/
https://www.ncbi.nlm.nih.gov/pubmed/29784924
http://dx.doi.org/10.1038/s41598-018-26221-x