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Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma
Constant exposure to allergen triggers destructive type 2 cell-mediated inflammation. The effect of allergen specific immunotherapy (SIT) in maintaining airway epithelial barrier function in asthma remains unknown. In the current study, we showed that SIT maintained airway epithelial homeostasis in...
Autores principales: | Yuan, Xiefang, Wang, Junyi, Li, Yin, He, Xiang, Niu, Bin, Wu, Dehong, lan, Nan, Wang, Xiaoyun, Zhang, Yun, Dai, Xi, Wang, Xing, Liu, Zhigang, Li, Guoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962552/ https://www.ncbi.nlm.nih.gov/pubmed/29784924 http://dx.doi.org/10.1038/s41598-018-26221-x |
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