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Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment
Prohibitin (PHB) was originally isolated and characterized as an anti-proliferative gene in rat liver. The evolutionarily conserved PHB gene encodes two human protein isoforms with molecular weights of ~33 kDa, PHB1 and PHB2. PHB1 and PHB2 belong to the prohibitin domain family, and both are widely...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962566/ https://www.ncbi.nlm.nih.gov/pubmed/29784973 http://dx.doi.org/10.1038/s41419-018-0661-3 |