Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy

Dysregulated miRNA expression and mutation of genes involved in miRNA biogenesis have been reported in motor neuron diseases including spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). Therefore, identifying molecular mechanisms governing miRNA expression is important to underst...

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Detalles Bibliográficos
Autores principales: Gonçalves, Inês do Carmo G., Brecht, Johanna, Thelen, Maximilian P., Rehorst, Wiebke A., Peters, Miriam, Lee, Hyun Ju, Motameny, Susanne, Torres-Benito, Laura, Ebrahimi-Fakhari, Darius, Kononenko, Natalia L., Altmüller, Janine, Vilchez, David, Sahin, Mustafa, Wirth, Brunhilde, Kye, Min Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962575/
https://www.ncbi.nlm.nih.gov/pubmed/29784949
http://dx.doi.org/10.1038/s41598-018-26347-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962575/
https://www.ncbi.nlm.nih.gov/pubmed/29784949
http://dx.doi.org/10.1038/s41598-018-26347-y

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