The structural basis of nanobody unfolding reversibility and thermoresistance

Nanobodies represent the variable binding domain of camelid heavy-chain antibodies and are employed in a rapidly growing range of applications in biotechnology and biomedicine. Their success is based on unique properties including their reported ability to reversibly refold after heat-induced denatu...

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Detalles Bibliográficos
Autores principales: Kunz, Patrick, Zinner, Katinka, Mücke, Norbert, Bartoschik, Tanja, Muyldermans, Serge, Hoheisel, Jörg D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962586/
https://www.ncbi.nlm.nih.gov/pubmed/29784954
http://dx.doi.org/10.1038/s41598-018-26338-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962586/
https://www.ncbi.nlm.nih.gov/pubmed/29784954
http://dx.doi.org/10.1038/s41598-018-26338-z

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