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The structural basis of nanobody unfolding reversibility and thermoresistance
Nanobodies represent the variable binding domain of camelid heavy-chain antibodies and are employed in a rapidly growing range of applications in biotechnology and biomedicine. Their success is based on unique properties including their reported ability to reversibly refold after heat-induced denatu...
Autores principales: | Kunz, Patrick, Zinner, Katinka, Mücke, Norbert, Bartoschik, Tanja, Muyldermans, Serge, Hoheisel, Jörg D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962586/ https://www.ncbi.nlm.nih.gov/pubmed/29784954 http://dx.doi.org/10.1038/s41598-018-26338-z |
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