Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury

Drug-induced liver injury remains a concern during drug treatment and development. There is an urgent need for improved mechanistic understanding and prediction of DILI liabilities using in vitro approaches. We have established and characterized a panel of liver cell models containing mechanism-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Wink, Steven, Hiemstra, Steven W., Huppelschoten, Suzanne, Klip, Janna E., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962642/
https://www.ncbi.nlm.nih.gov/pubmed/29502165
http://dx.doi.org/10.1007/s00204-018-2178-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962642/
https://www.ncbi.nlm.nih.gov/pubmed/29502165
http://dx.doi.org/10.1007/s00204-018-2178-z

Ejemplares similares