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Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury
Drug-induced liver injury remains a concern during drug treatment and development. There is an urgent need for improved mechanistic understanding and prediction of DILI liabilities using in vitro approaches. We have established and characterized a panel of liver cell models containing mechanism-base...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962642/ https://www.ncbi.nlm.nih.gov/pubmed/29502165 http://dx.doi.org/10.1007/s00204-018-2178-z |