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Efficacy of Colistin and Its Combination With Rifampin in Vitro and in Experimental Models of Infection Caused by Carbapenemase-Producing Clinical Isolates of Klebsiella pneumoniae

Despite the relevance of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) infections there are a scarce number of studies to evaluate in vivo the efficacy of combinations therapies. The bactericidal activity of colistin, rifampin, and its combination was studied (time–kill curves) against four...

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Detalles Bibliográficos
Autores principales: Pachón-Ibáñez, María E., Labrador-Herrera, Gema, Cebrero-Cangueiro, Tania, Díaz, Caridad, Smani, Younes, del Palacio, José P., Rodríguez-Baño, Jesús, Pascual, Alvaro, Pachón, Jerónimo, Conejo, M. Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962653/
https://www.ncbi.nlm.nih.gov/pubmed/29867823
http://dx.doi.org/10.3389/fmicb.2018.00912