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Efficacy of Colistin and Its Combination With Rifampin in Vitro and in Experimental Models of Infection Caused by Carbapenemase-Producing Clinical Isolates of Klebsiella pneumoniae
Despite the relevance of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) infections there are a scarce number of studies to evaluate in vivo the efficacy of combinations therapies. The bactericidal activity of colistin, rifampin, and its combination was studied (time–kill curves) against four...
Autores principales: | Pachón-Ibáñez, María E., Labrador-Herrera, Gema, Cebrero-Cangueiro, Tania, Díaz, Caridad, Smani, Younes, del Palacio, José P., Rodríguez-Baño, Jesús, Pascual, Alvaro, Pachón, Jerónimo, Conejo, M. Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962653/ https://www.ncbi.nlm.nih.gov/pubmed/29867823 http://dx.doi.org/10.3389/fmicb.2018.00912 |
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