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Foxp3(+) T Regulatory Cells: Still Many Unanswered Questions—A Perspective After 20 Years of Study

T regulatory (Treg) cells were discovered more than 20 years ago and have remained a topic of intense investigation by immunologists. The initial doubts about their existence were dissipated by the discovery in 2003 of the lineage specific transcription factor Foxp3. In this article, I will discuss...

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Detalles Bibliográficos
Autor principal: Shevach, Ethan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962663/
https://www.ncbi.nlm.nih.gov/pubmed/29868011
http://dx.doi.org/10.3389/fimmu.2018.01048