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Plasma Cell Alloantigen 1 and IL-10 Secretion Define Two Distinct Peritoneal B1a B Cell Subsets With Opposite Functions, PC1(high) Cells Being Protective and PC1(low) Cells Harmful for the Growing Fetus

B cells possess various immuno regulatory functions. However, research about their participation in tolerance induction toward the fetus is just emerging. Accumulating evidence supports the idea that B cells can play seemingly conflicting roles during pregnancy, either protecting or harming the fetu...

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Detalles Bibliográficos
Autores principales: Schumacher, Anne, Ehrentraut, Stefanie, Scharm, Markus, Wang, Hongsheng, Hartig, Roland, Morse, Herbert C., Zenclussen, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962664/
https://www.ncbi.nlm.nih.gov/pubmed/29868008
http://dx.doi.org/10.3389/fimmu.2018.01045