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Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy

Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking pathways. Through interactions with an array of proteins, such as myosin VI, huntingtin, Rab8, and Tank-binding kinase 1, as well as via its oligomerisation, optineurin has the ability to act as an a...

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Detalles Bibliográficos
Autores principales: Ryan, Thomas A., Tumbarello, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962687/
https://www.ncbi.nlm.nih.gov/pubmed/29867991
http://dx.doi.org/10.3389/fimmu.2018.01024