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SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4(+) T Lymphocytes

Targeted cancer immunotherapy with irradiated, granulocyte–macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that to be effective, these cell lines need to express i...

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Detalles Bibliográficos
Autores principales: Lacher, Markus D., Bauer, Gerhard, Fury, Brian, Graeve, Sanne, Fledderman, Emily L., Petrie, Tye D., Coleal-Bergum, Dane P., Hackett, Tia, Perotti, Nicholas H., Kong, Ying Y., Kwok, William W., Wagner, Joseph P., Wiseman, Charles L., Williams, William V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962696/
https://www.ncbi.nlm.nih.gov/pubmed/29867922
http://dx.doi.org/10.3389/fimmu.2018.00776