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Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct

A growing proportion of heart failure (HF) patients present with impairments in both ventricles. Experimental pressure-overload (i.e., transverse aortic constriction, TAC) induces left ventricle (LV) hypertrophy and failure, as well as right ventricle (RV) dysfunction. However, little is known about...

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Detalles Bibliográficos
Autores principales: Platt, Mathew J., Huber, Jason S., Romanova, Nadya, Brunt, Keith R., Simpson, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962732/
https://www.ncbi.nlm.nih.gov/pubmed/29867532
http://dx.doi.org/10.3389/fphys.2018.00472