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Left Atrial Appendage Thrombus Formation in a Patient on Dabigatran Therapy Associated With ABCB1 and CES-1 Genetic Defect

Dabigatran, directly targeting thrombin, is widely used for the prevention of stroke in nonvalvular atrial fibrillation (NVAF). We reported a rare case of left atrial appendage thrombus formation in a persistent NVAF patient despite the 31 months uninterrupted treatment with dabigatran 110 mg twice...

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Detalles Bibliográficos
Autores principales: Gu, Zhi-Chun, Ma, Xiao-Wei, Zheng, Xiao-Yuan, Shen, Long, Shi, Fang-Hong, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962821/
https://www.ncbi.nlm.nih.gov/pubmed/29867495
http://dx.doi.org/10.3389/fphar.2018.00491