Monoclonal antibody 3H11 chimeric antigen receptors enhance T cell effector function and exhibit efficacy against gastric cancer

Although chimeric antigen receptor T cell (CAR-T) therapies for certain types of solid tumors have been used in clinical trials, novel CARs that are able to target gastric cancer (GC) are still required. In our previous study, monoclonal antibody 3H11 (mAb 3H11), generated from immunization with fiv...

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Detalles Bibliográficos
Autores principales: Han, Haibo, Wang, Shanshan, Hu, Ying, Li, Zhaowei, Yang, Wei, Lv, Yunwei, Wang, Limin, Zhang, Lianhai, Ji, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962852/
https://www.ncbi.nlm.nih.gov/pubmed/29849787
http://dx.doi.org/10.3892/ol.2018.8255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962852/
https://www.ncbi.nlm.nih.gov/pubmed/29849787
http://dx.doi.org/10.3892/ol.2018.8255

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