Cargando…

Monoclonal antibody 3H11 chimeric antigen receptors enhance T cell effector function and exhibit efficacy against gastric cancer

Although chimeric antigen receptor T cell (CAR-T) therapies for certain types of solid tumors have been used in clinical trials, novel CARs that are able to target gastric cancer (GC) are still required. In our previous study, monoclonal antibody 3H11 (mAb 3H11), generated from immunization with fiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Haibo, Wang, Shanshan, Hu, Ying, Li, Zhaowei, Yang, Wei, Lv, Yunwei, Wang, Limin, Zhang, Lianhai, Ji, Jiafu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962852/ https://www.ncbi.nlm.nih.gov/pubmed/29849787 http://dx.doi.org/10.3892/ol.2018.8255

Ejemplares similares

SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer
por: Wang, Shanshan, et al.
Publicado: (2017)

Development and Characterization of Chimeric Anti‐carcinoembryonic Antigen Monoclonal Antibodies and Their Fab Fragments
por: Kamigaki, Takashi, et al.
Publicado: (1994)

Monoclonal antibodies and chimeric antigen receptor (CAR) T cells in the treatment of colorectal cancer
por: Jin, Ke-Tao, et al.
Publicado: (2021)

Validation of immunoassays for the Chlamydia trachomatis antigen Pgp3 using a chimeric monoclonal antibody
por: Goodhew, Brook, et al.
Publicado: (2023)

B cell depletion therapies in autoimmune diseases: Monoclonal antibodies or chimeric antigen receptor-based therapy?
por: Zhang, Zheng, et al.
Publicado: (2023)

Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells
por: SAKAI, Osamu, et al.
Publicado: (2021)

Chimeric Antigen Receptor (CAR)-Specific Monoclonal Antibody to Detect CD19-Specific T Cells in Clinical Trials
por: Jena, Bipulendu, et al.
Publicado: (2013)

Protocol for production and expression of chimeric bovine-human monoclonal antibodies
por: Heydarchi, Behnaz, et al.
Publicado: (2022)

Taking the Hinge off: An Approach to Effector-Less Monoclonal Antibodies
por: Valeich, Jamie, et al.
Publicado: (2020)

PSCA is a target of chimeric antigen receptor T cells in gastric cancer
por: Wu, Di, et al.
Publicado: (2020)

Monoclonal antibodies to neural antigens /
Publicado: (1981)

Modern Immunotherapy of Adult B-Lineage Acute Lymphoblastic Leukemia with Monoclonal Antibodies and Chimeric Antigen Receptor Modified T Cells
por: Maino, Elena, et al.
Publicado: (2015)

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody
por: Gulati, Sunita, et al.
Publicado: (2019)

Immune effector cell associated neurotoxicity syndrome in chimeric antigen receptor-T cell therapy
por: Sterner, Robert C., et al.
Publicado: (2022)

Long non-coding RNA SNHG1 suppresses cell migration and invasion and upregulates SOCS2 in human gastric carcinoma
por: Wang, Shanshan, et al.
Publicado: (2021)

Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer
por: Lv, Jiang, et al.
Publicado: (2019)

Generation of Monoclonal Antibodies against Highly Conserved Antigens
por: Zhou, Hongzhe, et al.
Publicado: (2009)

Preparation and Evaluation of Human-Murine Chimeric Antibody against Protective Antigen of Bacillus anthracis
por: Hao, Lina, et al.
Publicado: (2014)

Production, Binding and Cytotoxicity of Human/Mouse Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate
por: Yamaguchi, Toshiharu, et al.
Publicado: (1993)

Recognition of the Polypeptide Core of Mucin by Monoclonal Antibody MUSE11 against an Adenocarcinoma‐associated Antigen
por: Hinoda, Yuji, et al.
Publicado: (1990)

Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus
por: Kim, Pan Kyeom, et al.
Publicado: (2017)

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies
Publicado: (1987)

Antibody‐dependent Cytotoxicity Mediated by Chimeric Monoclonal Antibody Nd2 and Experimental Immunotherapy for Pancreatic Cancer
por: Nishihara, Tamahiro, et al.
Publicado: (2000)

Universal chimeric Fcγ receptor T cells with appropriate affinity for IgG1 antibody exhibit optimal antitumor efficacy
por: Zhu, Wen, et al.
Publicado: (2023)

Human monoclonal antibodies to lung-cancer antigens.
por: Sikora, K., et al.
Publicado: (1981)

First human study of a chimeric anti-methamphetamine monoclonal antibody in healthy volunteers
por: Stevens, Misty W, et al.
Publicado: (2014)

A Simple Methodology for Conversion of Mouse Monoclonal Antibody to Human-Mouse Chimeric Form
por: Dang, Vinh T., et al.
Publicado: (2013)

Establishment and Characterization of Mouse‐Human Chimeric Monoclonal Antibody to erbB‐2 Product
por: Ishida, Tadao, et al.
Publicado: (1994)

Novel chimeric monoclonal antibodies that block fentanyl effects and alter fentanyl biodistribution in mice
por: Ban, Bhupal, et al.
Publicado: (2021)

Chimeric Antigen Receptor (CAR)-Modified Immune Effector Cell Therapy for Acute Myeloid Leukemia (AML)
por: Acharya, Utkarsh H., et al.
Publicado: (2020)

Forecasting immune effector cell-associated neurotoxicity syndrome after chimeric antigen receptor t-cell therapy
por: Amidi, Yalda, et al.
Publicado: (2022)

Antibody Fc-chimerism and effector functions: When IgG takes advantage of IgA
por: Cottignies-Calamarte, Andréa, et al.
Publicado: (2023)

Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer
por: Cha, Jong-Ho, et al.
Publicado: (2022)

Expanded antigen-experienced CD160(+)CD8(+)effector T cells exhibit impaired effector functions in chronic lymphocytic leukemia
por: Bozorgmehr, Najmeh, et al.
Publicado: (2021)

Epitope analysis of monoclonal antibody NCRC-11 defined antigen isolated from human ovarian and breast carcinomas.
por: Price, M. R., et al.
Publicado: (1986)

Distribution of neocarzinostatin conjugated to biotinylated chimeric monoclonal antibody Fab fragments after administration of avidin.
por: Otsuji, E., et al.
Publicado: (1996)

Decreased Renal Accumulation of Biotinylated Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate after Administration of Avidin
por: Otsuji, Eigo, et al.
Publicado: (1997)

Preoperative Clinical Radioimmunodetection of Pancreatic Cancer by (111)In‐labeled Chimeric Monoclonal Antibody Nd2
por: Sawada, Tetsuji, et al.
Publicado: (1999)

Epitopes of carcinoembryonic antigen (CEA) defined by monoclonal antibodies.
por: Price, M. R.
Publicado: (1988)

Proceedings of an international workshop on monoclonal antibodies to tumour antigens.
Publicado: (1981)

Cannot write session to /tmp/vufind_sessions/sess_2to8hrfa0o27iu0pdr51uhldrc