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Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease

OBJECTIVE: To determine whether longitudinal change in white matter structural network integrity predicts dementia and future cognitive decline in cerebral small vessel disease (SVD). To investigate whether network disruption has a causal role in cognitive decline and mediates the association betwee...

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Detalles Bibliográficos
Autores principales: Lawrence, Andrew J., Zeestraten, Eva A., Benjamin, Philip, Lambert, Christian P., Morris, Robin G., Barrick, Thomas R., Markus, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962914/
https://www.ncbi.nlm.nih.gov/pubmed/29695593
http://dx.doi.org/10.1212/WNL.0000000000005551