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Effects of the cardiac myosin activator Omecamtiv-mecarbil on severe chronic aortic regurgitation in Wistar rats

BACKGROUND: Aortic regurgitation (AR) is a valvular disease that can lead to systolic heart failure. Treatment options besides cardiac surgery are limited and consequently severe AR is associated with higher mortality and morbidity when not operated. In this investigation, we examined the effects of...

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Detalles Bibliográficos
Autores principales: El-Oumeiri, Bachar, Mc Entee, Kathleen, Annoni, Filippo, Herpain, Antoine, Vanden Eynden, Frédéric, Jespers, Pascal, Van Nooten, Guido, van de Borne, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963065/
https://www.ncbi.nlm.nih.gov/pubmed/29783950
http://dx.doi.org/10.1186/s12872-018-0831-3