Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles

BACKGROUND: Multiple myeloma (MM) currently remains largely incurable. Cancer stem cells (CSCs) are believed to be responsible for drug resistance and eventual relapse. In this study, we exploited a novel agent to evaluate its inhibitory effect on MM CSCs. METHODS: Epirubicin (EPI)-loaded lipid micr...

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Detalles Bibliográficos
Autores principales: Shi, Fangfang, Li, Miao, Wang, Jing, Wu, Di, Pan, Meng, Guo, Mei, Dou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963075/
https://www.ncbi.nlm.nih.gov/pubmed/29784015
http://dx.doi.org/10.1186/s13287-018-0885-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963075/
https://www.ncbi.nlm.nih.gov/pubmed/29784015
http://dx.doi.org/10.1186/s13287-018-0885-2

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