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Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles
BACKGROUND: Multiple myeloma (MM) currently remains largely incurable. Cancer stem cells (CSCs) are believed to be responsible for drug resistance and eventual relapse. In this study, we exploited a novel agent to evaluate its inhibitory effect on MM CSCs. METHODS: Epirubicin (EPI)-loaded lipid micr...
Autores principales: | Shi, Fangfang, Li, Miao, Wang, Jing, Wu, Di, Pan, Meng, Guo, Mei, Dou, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963075/ https://www.ncbi.nlm.nih.gov/pubmed/29784015 http://dx.doi.org/10.1186/s13287-018-0885-2 |
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