Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action

In the human malaria parasite Plasmodium falciparum, membrane glutathione S-transferases (GST) have recently emerged as potential cellular detoxifying units and as drug target candidates with the artemisinin (ART) class of antimalarials inhibiting their activity at single-digit nanomolar potency whe...

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Detalles Bibliográficos
Autores principales: Lisewski, Andreas Martin, Quiros, Joel Patrick, Mittal, Monica, Putluri, Nagireddy, Sreekumar, Arun, Haeggström, Jesper Z., Lichtarge, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963095/
https://www.ncbi.nlm.nih.gov/pubmed/29324251
http://dx.doi.org/10.1016/j.ijpddr.2017.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963095/
https://www.ncbi.nlm.nih.gov/pubmed/29324251
http://dx.doi.org/10.1016/j.ijpddr.2017.12.003

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