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Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action
In the human malaria parasite Plasmodium falciparum, membrane glutathione S-transferases (GST) have recently emerged as potential cellular detoxifying units and as drug target candidates with the artemisinin (ART) class of antimalarials inhibiting their activity at single-digit nanomolar potency whe...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963095/ https://www.ncbi.nlm.nih.gov/pubmed/29324251 http://dx.doi.org/10.1016/j.ijpddr.2017.12.003 |