Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

BACKGROUND: Previous studies showed sanguinarine induced apoptosis in CRC cells but did not define the underlying mechanisms. The purpose of this work was to determine the in vivo and in vitro effects of sanguinarine on CRC tumors and to elucidate the mechanism in regulating the intrinsic apoptosis....

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Detalles Bibliográficos
Autores principales: Gong, Xianling, Chen, Zhihong, Han, Qinrui, Chen, Chunhui, Jing, Linlin, Liu, Yawei, Zhao, Liang, Yao, Xueqing, Sun, Xuegang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963096/
https://www.ncbi.nlm.nih.gov/pubmed/29783958
http://dx.doi.org/10.1186/s12885-018-4463-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963096/
https://www.ncbi.nlm.nih.gov/pubmed/29783958
http://dx.doi.org/10.1186/s12885-018-4463-x

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