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The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model
BACKGROUND: Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, causing a major risk of liver disease and hepatocellular carcinoma (HCC). Many mouse models have been tried to establish HBV infection through injection with various HBV-containing plasmids. However,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963156/ https://www.ncbi.nlm.nih.gov/pubmed/29783985 http://dx.doi.org/10.1186/s12985-018-1002-y |