The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

BACKGROUND: Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, causing a major risk of liver disease and hepatocellular carcinoma (HCC). Many mouse models have been tried to establish HBV infection through injection with various HBV-containing plasmids. However,...

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Detalles Bibliográficos
Autores principales: Wang, Xian, Zhu, Jianmin, Zhang, Yong, Li, Yue, Ma, Tai, Li, Qun, Xu, Jiegou, Xu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963156/
https://www.ncbi.nlm.nih.gov/pubmed/29783985
http://dx.doi.org/10.1186/s12985-018-1002-y

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