Regulation of Large Number of Weak Targets—New Insights from Twin-microRNAs

Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the “small...

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Detalles Bibliográficos
Autores principales: Zhao, Yixin, Lin, Pei, Liufu, Zhongqi, Yang, Hao, Lyu, Yang, Shen, Xu, Wu, Chung-I, Tang, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963297/
https://www.ncbi.nlm.nih.gov/pubmed/29688430
http://dx.doi.org/10.1093/gbe/evy079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963297/
https://www.ncbi.nlm.nih.gov/pubmed/29688430
http://dx.doi.org/10.1093/gbe/evy079

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