Cargando…
Regulation of Large Number of Weak Targets—New Insights from Twin-microRNAs
Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the “small...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963297/ https://www.ncbi.nlm.nih.gov/pubmed/29688430 http://dx.doi.org/10.1093/gbe/evy079 |