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SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway

SIRT3 is a class III histone deacetylase that modulates energy metabolism, genomic stability and stress resistance. It has been implicated as a potential therapeutic target in a variety of neurodegenerative diseases, including Parkinson’s disease (PD). Our previous study demonstrates that SIRT3 had...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Deng, Yong-Ning, Zhang, Jing-Yi, Liu, Jie, Li, Yan-Bo, Su, Hua, Qu, Qiu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963348/
https://www.ncbi.nlm.nih.gov/pubmed/29896416
http://dx.doi.org/10.14336/AD.2017.0517