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Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients

Melanoma is an aggressive cancer with highly metastatic ability. We propose cofilin-1, a key protein in the regulation of actin dynamics and migration, as a prognostic marker. We determined cofilin-1 levels in a retrospective cohort of patients with melanomas and benign lesions of melanocytes (nevi)...

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Detalles Bibliográficos
Autores principales: Bracalente, Candelaria, Rinflerch, Adriana R., Ibañez, Irene L., García, Francisco M., Volonteri, Victoria, Galimberti, Gastón N., Klamt, Fabio, Durán, Hebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963619/
https://www.ncbi.nlm.nih.gov/pubmed/29844875
http://dx.doi.org/10.18632/oncotarget.25303