Ocular Distribution and Pharmacokinetics of Lifitegrast in Pigmented Rabbits and Mass Balance in Beagle Dogs

Purpose: Lifitegrast is approved in the United States for the treatment of dry eye disease (DED). We assessed lifitegrast's ocular distribution/pharmacokinetic profile in rabbits, and (14)C-lifitegrast mass balance/excretion in dogs. Methods: Female pigmented rabbits received a single topical o...

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Detalles Bibliográficos
Autores principales: Chung, Jou-Ku, Spencer, Elizabeth, Hunt, Matthew, McCauley, Thomas, Welty, Devin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963635/
https://www.ncbi.nlm.nih.gov/pubmed/29267138
http://dx.doi.org/10.1089/jop.2017.0106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963635/
https://www.ncbi.nlm.nih.gov/pubmed/29267138
http://dx.doi.org/10.1089/jop.2017.0106

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