Bioavailability of Oral Hydrocortisone Corrected for Binding Proteins and Measured by LC-MS/MS Using Serum Cortisol and Salivary Cortisone

CONTEXT: The assessment absolute bioavailability of oral hydrocortisone is complicated by its saturable binding to cortisol binding globulin (CBG). Previous assessment of bioavailability used a cortisol radioimmunoassay which has cross reactivity with other steroids. Salivary cortisone is a measure...

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Detalles Bibliográficos
Autores principales: Johnson, TN, Whitaker, MJ, Keevil, B, Ross, RJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963674/
https://www.ncbi.nlm.nih.gov/pubmed/29795974
http://dx.doi.org/10.4172/jbb.1000365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963674/
https://www.ncbi.nlm.nih.gov/pubmed/29795974
http://dx.doi.org/10.4172/jbb.1000365

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