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Bioavailability of Oral Hydrocortisone Corrected for Binding Proteins and Measured by LC-MS/MS Using Serum Cortisol and Salivary Cortisone

CONTEXT: The assessment absolute bioavailability of oral hydrocortisone is complicated by its saturable binding to cortisol binding globulin (CBG). Previous assessment of bioavailability used a cortisol radioimmunoassay which has cross reactivity with other steroids. Salivary cortisone is a measure...

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Detalles Bibliográficos
Autores principales:	Johnson, TN, Whitaker, MJ, Keevil, B, Ross, RJ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963674/ https://www.ncbi.nlm.nih.gov/pubmed/29795974 http://dx.doi.org/10.4172/jbb.1000365

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