TALEN-Mediated FLAG-Tagging of Endogenous Histone Methyltransferase DOT1L

Histone modification including H3 lysine 79 methylation (H3K79me) plays a key role during gene transcription and DNA damage repair. DOT1L, the sole methyltransferase for three states of H3K79me, is implicated in leukemia, co-lorectal cancer, and dilated cardiomyopathy. However, understanding of DOT1...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Cheng, Zhu, Guangjing, Martos, Suzanne N., Feng, Xue, Zhang, Haimou, Jia, Yankai, Wang, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963693/
https://www.ncbi.nlm.nih.gov/pubmed/29796335
http://dx.doi.org/10.4236/abb.2017.89023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963693/
https://www.ncbi.nlm.nih.gov/pubmed/29796335
http://dx.doi.org/10.4236/abb.2017.89023

Ejemplares similares