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SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression

Acute lymphoblastic leukemia (ALL) is associated with significant morbidity and mortality, necessitating further improvements in diagnosis and therapy. Targeted therapies directed against chromatin regulators are emerging as promising approaches in preclinical studies and early clinical trials. Here...

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Detalles Bibliográficos
Autores principales: Lin, Chiou-Hong, Wong, Stephen Hon-Kit, Kurzer, Jason H., Schneidawind, Corina, Wei, Michael C., Duque-Afonso, Jesús, Jeong, Johan, Feng, Xuhui, Cleary, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963704/
https://www.ncbi.nlm.nih.gov/pubmed/29694893
http://dx.doi.org/10.1016/j.celrep.2018.03.124