Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels

Sphingosine-1-phosphate (S1P) is an important lipid signalling molecule. S1P is produced via intracellular phosphorylation of sphingosine (Sph). As a lipid with a single fatty alkyl chain, Sph may diffuse rapidly between cellular membranes and through the aqueous phase. Here, we show that the absenc...

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Detalles Bibliográficos
Autores principales: Riento, Kirsi, Zhang, Qifeng, Clark, Jonathan, Begum, Farida, Stephens, Elaine, Wakelam, Michael J., Nichols, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963794/
https://www.ncbi.nlm.nih.gov/pubmed/29787576
http://dx.doi.org/10.1371/journal.pone.0197401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963794/
https://www.ncbi.nlm.nih.gov/pubmed/29787576
http://dx.doi.org/10.1371/journal.pone.0197401

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